Monthly Archives: April 2007

Premature Ejaculation – The Most Common Male Sexual Problem, Get Deferol and Get in Control

Guys, found a new consumer product to achieve ejaculatory control – Copy FYI. I’ve been taking it daily for 2 weeks now and it certainly works for me in delaying my time to orgasm. My wife is very pleased that I’m no longer a “sprinter” in bed. Here’s some info.

SEX – CAN IT LAST LONGER ?
THE SOLUTION TO THE MOST COMMON MALE SEXUAL PROBLEM


Consumer Product Developed for Male Climax Control
DOVER, Delaware (April 20, 2001) PRNewswire — IDIST Laboratories, LLC announced that it has released for consumer purchase a product that helps promote greater climax (ejaculatory) control in men and allows for longer-lasting and more mutually satisfying sexual intercourse. Deferol Climax Control Supplement is a patent pending, clinically tested product that is the first science-based consumer product to be introduced as a male climax control supplement.

Early ejaculation, premature ejaculation (PE), and lack of ejaculatory control are reported to be the most common sexual difficulties in men. According to American Family Physician, “up to 40% of U.S. males have difficulties with premature ejaculation (PE) or lack of ejaculatory control at some time in their lives”. Other surveys have reported that between 30-60% of men have intermittent concerns about ejaculating too rapidly. Currently, there is no FDA-approved prescription drug for the treatment of premature ejaculation or climax control problems.

“This is a very significant problem affecting at least one-third of all sexually active men,” stated Christopher P. Steidle, M.D., a urologist and leading sexual medicine researcher with Northeast Indiana Research in Fort Wayne. Dr. Steidle is the author of The Impotence Sourcebook, Testosterone — A Users Manual and author of the WellnessWeb.com article Ejaculatory Disorders. “Until the availability of Deferol, the only useful alternative physicians had to offer men with ejaculatory control problems was to prescribe SSRI-type anti-depressant drugs on an off-label basis. Like Deferol, these prescription anti-depressant drugs work by increasing brain serotonin and decreasing anxiety, however, the prescription drugs are not without their drawbacks,” said Dr. Steidle.

As with other types of sexual problems, early ejaculation and a lack of ejaculatory control can cause significant stress and dissatisfaction for both partners and may be disruptive to marriages and other relationships. “A surprising percentage of women complain to their physicians that their partner is unable to perform sexual intercourse for a satisfactory amount of time,” said Dr. Steidle, also co-author of The Female Sexual Dysfunction Treatments. “A man’s lack of ejaculatory control can sometimes undermine an otherwise healthy relationship.”

Initial consumer studies were conducted last year with both “on-demand” (when needed), and chronic daily use of Deferol. In those studies, the intravaginal latency period for ejaculation (time to climax during intercourse) was significantly improved after use of Deferol. David M. Ferguson, Ph.D., M.D., in collaboration with a group of urologists nationwide, plans to conduct additional studies with Deferol. Dr. Ferguson is a prominent medical researcher in Chicago specializing in clinical trial protocol development and has substantial expertise in both male and female sexual medicine research.

“There is strong scientific evidence in the medical literature that supports the Deferol formulation which, by design, utilizes the same proven pathway that prescription SSRI anti-depressants use as part of its activity,” said Dr. Ferguson. “Independent animal laboratory studies have already demonstrated that ingredients in Deferol significantly delay time to ejaculation.”

Deferol was formulated by pharmacists, pharmaceutical scientists, and sexual health researchers, holding U.S. and international patents involving serotonin, to address the principal factors that contribute to a lack of ejaculatory control in men. “Unlike anti-depressants, Deferol was designed to briefly, but naturally, elevate central levels of serotonin and also deliver a specific natural anti-anxiety compound,” said Martin G. Crosby, R.Ph., co-inventor of Deferol. “Together, the proprietary combination of ingredients in Deferol helps to significantly improve ejaculatory control and combat the anxiety that can cause early ejaculation. Deferol’s unique formulation helps delay male sexual climax in a safe, non-prescription manner.”

Deferolis now available to consumers via a confidential purchasing procedure through the Company’s website and through a highly respected consumer health website. Both websites have extensive patient education materials about premature ejaculation and lack of ejaculatory control. Because Deferol is a supplement, obtaining it does not require visiting a physician or obtaining a prescription.

Deferol is the discreet solution to what can be an embarrassing issue for many men. For more information or to purchase Deferol, please visit www.deferol.com, www.wellnessweb.com, or call 1-800-213-0300.

About IDIST Laboratories, LLC IDIST Laboratories, LLC is a science-based consumer products company engaged in commercializing innovative proprietary consumer products to improve quality of life for men and women, with an initial strategic focus on sexual health issues. In addition to Deferol Climax Control Supplement, the Company’s current product development pipeline includes a series of proprietary sexual health and sexual enhancement consumer products.

Deferol Climax Control Supplement is not a drug, and the statements in this press release have not been evaluated by the FDA. Deferol Climax Control Supplement is not intended to diagnose, treat, cure, or prevent any disease. Deferol Climax Control Supplement is a unique natural formulation intended to promote greater climax control in men and allow for longer-lasting sex.

Pelvic inflammatory disease

Pelvic Inflammatory Disease or PID is an infection from the vaginia or cervix
to the uterus, fallopian tubes and broad ligaments.

symtoms: vaginal discharge, anorectal pain, abdominal pain, nausea, vomiting,
fever.

Almost any bacteria may cause PID, most common is chlamydia. Other causes:
sexual intercourse with a man with urethritis, insertion of an IUD, abortion,
or childbirth.

Early therapy with appropriate antibiotics is important: PID’s can cause
infertility.

Sexually transmitted disease (STD) constitutes a staggering public health
problem in the U.S. According to the government’s Centers for Disease
Control, 15 million new cases are diagnosed annually. Young people aged 15
to 29 have the highest rates of infection. By the age of 21, almost one
American in five requires treatment for a disease acquired through sexual
contact. Among teenagers who are sexually active, the infection rate is a
whopping one in four.

Sexually transmitted diseases are more than just a nuisance. Some of these
diseases may be fatal, particularly to women and their unborn babies. Other
STDs cause pelvic inflammatory disease, tubal pregnancy, sterility, certain
types of cancer, or blindness. Babies whose mothers are infected with STDs
may suffer from birth defects or mental retardation.

Although the rates of disease and disability from sexually acquired
illnesses are highest among the poor, the impact of STDs on health care
spending touches all income levels. As far back as the mid-nineties, the
direct and indirect costs of the major STDs and their complications were
estimated to total almost $17 billion annually.

During the 1970s, the government monitored just five sexually transmitted
diseases — syphilis, gonorrhea, chlamydial infection/nongonococcal
urethritis, pelvic inflammatory disease, and genital herpes/warts.

In the 1980s, however, the mounting AIDS epidemic triggered an explosion of
research into and monitoring of diseases that were transmitted sexually. The
painstaking study of AIDS taught scientists a great deal about other STDs;
and today the federal government recognizes some 50 types of sexually
transmitted infection.

Thanks to public awareness campaigns, many people now know how to protect
themselves from the AIDS virus by avoiding injection drug use and by
faithfully using “safer sex” techniques. Fortunately, this same approach
also protects them from the many other disease agents transmitted through
sexual contact or some other transfer of bodily fluids.

58-year-old man with chronic Lyme disease

At Internal Medicine Grand Rounds on February 14, 2002, Allen C. Steere, MD,
discussed a 58-year-old man with chronic Lyme disease.1 The patient, Mr C,
described 10 years of symptoms following spending time on Martha’s Vineyard, an
area endemic for Lyme disease. He reported an episode of left-sided Bell’s
palsy and subsequently noted that he was less competent mentally and that he
had developed numerous physical symptoms including neck pain, back pain, joint
aches, periodic blurred vision, and periodic sweats. He was treated for Lyme
disease with an initial course of tetracycline and his symptoms improved.

However, his symptoms returned a few years later, and he received multiple
subsequent courses of antibiotics for Lyme disease. In late 1999, due to a
change in his insurance, Mr C transferred to a new primary care physician, Dr
N. His new physician was not convinced of the benefit of recurrent courses of
antibiotics and wondered whether Mr C was suffering from depression. He
prescribed paroxetine, 20 mg/d. On that regimen, Mr C noted less anxiety, less
joint pain, and improved cognition. He was also sleeping better.

Dr Steere discussed the epidemiology, clinical manifestations, diagnostic
testing, and treatment for Lyme disease. He also discussed the post-Lyme
disease syndrome or chronic Lyme disease. He suggested that Mr C’s symptoms fit
within the spectrum of chronic fatigue syndrome or fibromyalgia, even though
his symptoms did not fall precisely within the definitions of either. However,
regardless of whether his illness is called chronic Lyme disease or chronic
fatigue, he suggested the treatment would be similar. He suggested use of
low-dose tricyclic drugs such as amitriptyline, nonsteroidal anti-inflammatory
drugs for joint or muscle pain, and selective serotonin reuptake inhibitors for
patients with depression or anxiety. Most important was a regular routine
including modest physical activity.

MR C, THE PATIENT

My condition is improving one way and seems to be moving in a different
direction. I still have confusing days and moments when I have difficulty
adding and doing simple things mentally. They are happening less frequently,
but it still does happen monthly or every couple of months. I still have
swelling in my neck, elbows, and ankles. However, it is occurring less
frequently. The rashes still occur. I recently saw a dermatologist for this
problem and was diagnosed with a form of psoriasis, and I was started on
photochemotherapy, which is helping.

DR N, THE PHYSICIAN

I last saw Mr C in March of this year. He was feeling pretty well overall and
states that he is “doing much better.” In terms of his musculoskeletal issues,
he reports mild left ankle swelling and discomfort. He feels his cognitive
function is “95%,” but on some days he describes “slightly fuzzy” thinking, and
on others feels normal. He saw a dermatologist for a rash, and a biopsy
revealed a variant of psoriasis (parapsoriasis) that can progress to cutaneous
T-cell lymphoma. He is being treated with photochemotherapy. He remains on
quinapril (10 mg/d), atorvastatin (10 mg/d), and paroxetine (20 mg/d).

REFERENCES

1. Steere AC. A 58-year-old man with a diagnosis of chronic Lyme disease. JAMA.
2002;288:1002-1010.

Emerging infectious diseases

I am trying to get information about emerging infectious diseases
(either those that appear due to deforestation or due to urbanization). I
really do not want to write about HIV, as my life seems consumed with it in
evry other arena. Some have suggested Ebola zaire, and Cryptosporidium, but I
was wondering if there were any that were clearly emerging because of human
encroachment on sylvan ecology.

Also – what is the etiologic agent of Toxic Shock Syndrome


Staphylococcus aureus is the etiological agent of Toxic Shock
Syndrome. Specifically, it’s a strain of S. aureus that produces
toxic shock syndrome toxin (TSS-1). (TSS does have other, less
common etiologies, however.)

TSS-1, among other things, is a powerful stimulus to macrophages
causing them to produce IL1 (which probably accounts for much of the
high fevers).

Toxic Shock Syndrome is caused by a toxin whose gene is carried on a
plasmid in Staphylococcus aureus bacteria.

May I suggest you consider the following topics for your report:
Tuberculosis — resurgence in number of cases, especially among
those housed in homeless shelters, prisons, and other areas of crowding
and/or poor hygiene; this is leading to the increase of multiple-drug
resistance strains.
Necrotizing faciitis due to Streptococcus pyogenes — the so-
called “flesh-eating” bacteria; was probably the agent which infected
Muppet creator Jim Henson.
Rabies virus is clearly abundant worldwide and is becoming a
major concern in much of Texas and probably all along the Mexican
border.
The potential of diseases such as cholera or plague entering
North America due to transport of infected persons via rapid world-
linking air travel.
Hemorrhagic Escherichia coli — food poisoning (e.g. Jack In the
Box – Oregon/Washington a couple of years ago)
Increasing drug resistance of several bacteria, most notably
Staphylococcus aureus and Enterococcus resistance to vancomycin.

How about the emerging Vancomycin resistant strains of organisms that
are lurking at this point in time. I read about them being a problem in
the Easter USA just recently. In our O.R. we are using quite a bit of
Vancomycin… it is a scary thought that these organisms might appear at
our facility. The articles I read were regarding a new drug under
testing by the FDA. They are allowing some use for this type of case,
but I guess a Vanco resistant organism is pretty well-off… hard to
kill.

How about plague. Was that a new form of whooping cough in
Texas? Crowd animals and they start passing diseases. I like the TB
suggestion. In Oakland the testing positive rate is 5% in high school
students.

Anything that requires a resonable level of sanitation. I’d bet
we’re having a real increase in food poisoning in the U.S. From the chicken
factories to the slaughterhouses the food quality is decreasing. What do
you get when you let the company pay the inspector? Probably not too many
write-ups.

Aids is a man-made disease?

The following came from NEXUS magazine Feb-March 1994 issue:

IS AIDS A MAN-MADE DISEASE?

The author (Dr. Robert Strecker; Los Angeles; Strecker Group) of the above
article claims that Aids was engineered ON PURPOSE, beginning in 1969
when the DoD requested $10 million to produce viruses that could
selectively destroy the immune system. He claims that AIDS’s “base”
genes comes from two retroviruses; the Bovine Leukaemia virus (in
cattle) and the Bovine Visna virus (in sheep). He goes on to state that
these two retroviruses were grown in culture plates of human tissue in
1972 by the U.S. National Institute of Health by a guy named Stuart Aronson.

Near the end of the article he invokes the name of GLOBAL 2000 and the
genocide of 2/3 of the human race as their goal….

Weird stuff, but then again, NEXUS is FATE magazine to the ^10th power…

Speaking as a medicinal chemist, I see red whenever I hear the “AIDS is
man-made” business. We truly don’t know beans about viruses, not enough to make
them, not enough to breed them to specific diseases. This is hard for many
people outside the medical field to swallow, since viral diseases are so
common. Me, I wouldn’t even say the darn things are alive. Living systems are
even harder to figure out, of course, so maybe that’ll help us to figure out
all there is to know about the simplest virus. . .say, about 75 years after I’m
dead.

And we *definitely* didn’t know beans about them in 1969, as the original
post’s source claims. The only thing that makes me hop around the room even
more than this one is the one about “The drug companies have cures for AIDS (or
whatever), but they’re holding ’em back until *everybody* gets it.”

As a recidivist biologist I’ll give this a try. The proposal you mention is
effectively impossible for the following two reasons:

1) Most viruses replicate with the help of a host cell. If the virus and
host cell are not sufficiently well matched already, they cannot replicate.
This means the virus cannot mutate either (since mutation doesn’t exist
except as part of the replication process).

2) If the proposed method of viral proliferation _were_ possible, you’d see
versions of every animal disease with viral origins in humans and (probably)
a counterpart to every human viral disease in animals. The latter is
certainly not the case since we’ve been actively looking for AIDS-like
diseases in populations of other species, both as a source of test animals
and to see what natural defenses those populations might have developed.
Any (active) biologist worth his/her salt can name MANY viral diseases
present in other species that have not been found in humans.

The first human retrovirus was isolated in 1978, the second in 1982. When
the third virus was found in 1983 and this turned out to be the much sought
agent. The other two human retrovirii both cause rare forms of Leukemia.
Considering that Leukemia and AIDS have largely opposing effects this was
rather surprising.

In the ’60’s retroviruses were still little more than laboratory
curiousities and were not thought to have much relavence to the transmission
of cancers in animals in uncontrolled situations. Certainly there seemed
little likelyhood then that they had any relavence to diseases in humans.

The Feline leukemia virus was first discovered in the early 1960’s as
causing disease in natural populations of an animal.

The people who invented HIV must have been incredibly prescient to use
two incredibly rare and poorly studied retro-virusii to invent their killer
disease. It’s not like there were hundreds to choose from, two sounds
like about all they had! So we have some top scientists, paid millions
of dollars to take all the known examples of the most obscure type of
virus, which was little more than a scientific curiousity and randomly
inject them into some animal and they would then magically produce a killer
disease capable of wiping out 2/3’s of the population of an unrelated animal?

Not only this but the main thrust of research into retrovirii was in the
ubiquitous endogenous retrovirii, not the rare exogenous ones which seem
now to be the ones which cause illness.

Until the discovery of reverse transcriptase in 1970 it wasn’t even clear
_how_ retroviruses could interact with the genes of the host to produce
a malignant effect.

Really, the hypothetical HIV manufacturers would have been very unlikely to
pick on retrovirii as their building blocks. Far better to use more easily
understood and plentiful viruses of other types.

Why did it take so long from people to discover it?

Research started in the 1970’s when it became clear that something was
affecting large groups of Africans and some people outside that continent,
predominantly male homosexuals. The disease was unusual in it’s affects and
death was usually caused by opportunist infections. This made it harder to
isolate the virus involved.

Once the virus was isolated it was possible to study blood samples from
long dead patients who died of mystery diseases to discover if they died
of the same thing.

There are far to many lines of evidence which point against a man-made
origin for the idea to have any credibility. It simply isn’t man made.

Lesbians Not Immune to Sexually Transmitted Diseases

LONDON (Reuters) – Lesbians are just as likely as heterosexual women
to get sexually transmitted diseases such as
hepatitis and genital herpes, Australian researchers said on
Tuesday.

Since hepatitis is also an injected-dope disease, all that likely means is
that lesbians are as likely to use injected dope as are straight women.
Genital herpes? It spreads just fine mouth-to-genital or genital-to-mouth,
whether you are straight, gay, or lesbian. (Monica may have acquired the First
Boyfriend’s herpes that way – remember how he told her at times he couldn’t
have oral sex with her, because his herpes was acting up?)

“We demonstrated a higher prevalence of bacterial vaginosis (vaginal
disease), hepatitis C and HIV risk behaviors in women
who have sex with other women compared with (other women),” Dr
Katherine Fethers said in a report in the journal Sexually
Transmitted Infections.

Just what does this really mean?
Does it just mean the well-known (among lesbians) fact that a major HIV risk
factor – needle drug use – is more common among lesbians than among straight
women?

She and her colleagues said only 7% of the women who had female sex
partners said they had never had sex with a man.

Like gay men, lesbians often don’t accept themselves until after a
considerable period of straight dating – and, unfortunately often marriage.
It would thus be surprising if typical lesbians had “never” had sex with a
man – not even when in their early teens.

The rich man’s disease

I always thought no one outside of overblown Victorian romances
got gout, but recently a good friend came down with it and it’s
not after all very funny. Who knew?

I get it in my right foot every now and then and it’s quite painful.
Luckily, there are some good medications for it these days.

I understand that an excessive fondness for steak can lead to it.
Ah, yes — the rich man’s disease.

No, steak doesn’t have much of an impact on it. Liver or kidneys can
contribute.

Nor is it a “rich man’s disease.” Rich men go to the doctor and get
diagnosed for gout. Poor people simply have “the miserables”. As Alan
King once noted, “You never heard of a poor man hospitalized for
exhaustion.”

I wasn’t really serious, although it certainly is known as the “rich man’s
disease”. Poor people never had the chance to eat well enough to fall
victim to it, was the belief. Coincidentally, just last weekend I was with
a man who was suffering with it and made no bones about it. Noisily.
Filthy rich, he was, too.

As for diagnosing it, sure, they know what it is. Curing it is the problem,
and the pain is quite stubborn also, I’m told.

Another victim was my lead-man, way back when I first hired in at Lockheed.
He was in his twenties and hailed from Bohemia. He complained a lot also.